However, as late as 2019, the actress was adamant that she wasn't going to end her wedding in a divorce.
"I don't know why it's difficult for other people, but Danny and I have always loved each other and we have three amazing children together," Perlman said during an episode of Watch What Happens Live with Andy.
She continued, "You know, we were together for 40 years. 40 years is a long time, you might have to do something else!"
Perlman shared that her relationship with her husband of 30 years was much better since the separation because "all the tense stuff" was gone.
Perlman and DeVito began dating in 1971, and their wedding was in January 1982. The pair have three children together: Lucy, Grace, and Jacob, all of whom are adults now.