Following his and Jenny’s divorce, Bobby started dating again. In 2012, a mutual friend introduced him to Rose Byrne, and they soon hit it off. Although rumors swirled that they were a couple at the end of 2012, Bobby and Rose didn’t go public until their red carpet debut at the CFDA Fashion Awards in June 2013, per People. Since then, the couple has maintained a successful personal and professional relationship.

During their romance, Bobby and Rose have co-starred together in multiple films, including Annie, Adult Beginners, Spy, Martha the Monster, and their 2019 Broadway debut in Medea, per Vanity Fair. While some would find working with your partner daily awkward, the actors don’t seem to mind. In September 2022, Deadline announced that the couple would co-star with Robert De Niro in the road trip comedy, Inappropriate Behavior.

Although Bobby and Rose have a solid working relationship, they're both more proud of two other collaborations. On Feb. 1, 2016, the couple welcomed their first son, Rocco Robin. One year later, Rose gave birth to her and Bobby’s second son, Rafael.

Bobby and Rose have remained “private” about their relationship but have opened up about their marital status through the years. The couple has never been married and seemingly aren’t in a rush to do so, despite calling each other “husband and wife.” Rose also wears two bands on her wedding ring finger but said other milestones caused her and Bobby not to get legally married. Nonetheless, the couple feels the title “husband and wife” perfectly fits their relationship.

“I hate all the other words! It's just easier to say 'husband and wife,'" Cannavale told Vulture in 2020. "'Boyfriend and girlfriend' feels so young. 'Partner' feels so sterile."

He added, "What else could we say?" he asked Byrne before jokingly answering, "My lover!” to which Rose replied, "Sure, my lover, Bobby."

Bobby ended the conversation by saying, “Who gives a s--t?!" and declared, "It's just funny what people care about."