At the end of the fourth episode of The Last of Us, Ellie and Joel are camped out in a high rise in Kansas City where they wake up to discover that Henry and his brother Sam have guns trained on them. The episode ends there, although we've heard a character named Kathleen refer to Henry several times earlier in the episode.

As the TV show unfolds, it has made changes to the game on which it's based. Henry and Sam are from the game, but their context has been changed on the show.

In the game, Henry and Sam are two brothers, and Henry is fiercely protective of Sam. The two are from Hartford originally, and they meet Joel and Ellie in Pittsburgh. Henry and Sam ran into Hunters in the city, which is why they have been forced to hide out there. The four of them ultimately decide to team up to get out of Pittsburgh, and they eventually learn that they are all headed west in search of the Fireflies.