On the Feb. 8, 2024 now-infamous episode Club Shay Shay, Mo’Nique explained that she was not comfortable with a would-you-rather question posed to her on an episode of D.L. Hughley’s radio show. Mo’Nique had reached out to D.L. to explain her feelings on the would-you-rather situation. It did not go well. Mo’Nique ended up sending a cease and desist to prevent the show from airing. This was the impetus for all future issues between the two comics.

Later in the Club Shay Shay clip she talks about D.L. and her sharing comedy bills, D.L. pulling out of bills, D.L. demanding headliner status, and more that led to speaking out about D.L.'s daughter via an Instagram post. On June 3, 2022, she wrote, "When my husband & I say we have to fight for the little girls coming up behind us & u see DL didn’t believe his own daughter over a friend, because he seemingly likes his friend more than he LOVED HIS OWN DAUGHTER & didn’t want to be bothered by the inconvenient truth."

Mo'Nique apologized to D.L. Hughley's family on stage at a June 19, 2022 show at the Duke Energy Center of Performing Arts in Raleigh, N.C. She definitely did not apologize for anything she said about D.L. Hughley.