Sadly, Jenna only survived the witches, werewolves, and vampires of Mystic Falls until the Season 2 episode "The Sun Also Rises." Klaus (Joseph Morgan) killed her for his ritual to reverse the werewolf / vampire hybrid curse. And in doing so, he also turned her into a vampire. But shortly after that, he drove a stake through her heart, cementing her tragic death.

Her death led to Alaric (Matthew Davis) briefly drinking himself into a grief-stricken stupor before he took on the role of guardian for Elena and Jeremy and moved into the Gilbert household. Afterward, Jenna appeared on and off through other episodes of The Vampire Diaries, though in those cases, it was through memories or hallucinations. For her, there was no bringing her back from the dead or reversing some spell.