Pence was raised Roman Catholic and was baptized at St. Columba in Columbus, Ind., where he and his brothers served as altar boys and attended parochial school, as The New York Times reported in 2016. They also attended church six days a week, if not seven.

“Our life revolved around the church,” one of his older brothers told the Times.

Once we got to Hanover College, however, Pence “began to meet young men and women who talked about having a personal relationship with Jesus Christ,” as he recalled to CBN News in 2010. “That had not been a part of my experience.”

"Standing at a Christian music festival in Asbury, Ky., in the spring of 1978, I gave my life to Jesus Christ and that’s changed everything," he added.

After graduating from Hanover, Pence identified as an “evangelical Catholic” as he struggled to reconcile his Catholic experience with his changing religious beliefs, per the Times.

Pence’s wife, Karen, was also “very much a part of his faith journey,” as Mark Bailey, a former law colleague of Pence’s, told the newspaper. The couple, who met during his years studying law at Indiana University, were attending an evangelical church in Indianapolis, Ind., by the mid-1990s.

Now Pence is the only one of his parents’ six children who isn't Catholic. And his mother, Nancy, was disappointed by his religious shift, according to Rev. Clement T. Davis, the priest at the family’s church. “You could see Nancy just shake her head about it,” he told the Times. “She was disappointed. She had hoped he could find his way back to the church.”