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Along with his siblings Joe and Angela, Anthony Russo grew up in Cleveland, Ohio. Their mother Patricia was a stay-at-home mom, while their father Basil Russo was a former judge. He attended Benedictine High School and afterwards received his degree from the University of Iowa. The Case Western Reserve University was attended by both brothers. With “Pisces,” their first independent feature film, they launched their career as a writer-director-producer team while still students at CWRU.